Abdominal ultrasound in paraneoplastic Pyoderma gangrenosum caused by renal carcinoma

Ioana Duca, Flaviu Rusu, Nicolae Nicula, Dan Lucian Dumitrascu

Abstract


We present the case of a 60-year-old male patient, with refractory ulcers in the groin. Ultrasoundand CT showed a large vascularized tumor of the kidney with cystic parts and inhomogeneous dynamic behaviour. Histology demonstrated Pyoderma gangrenosum (ulcer) and well differentiated adenocarcinoma (kidney).

Pyoderma gangrenosum appears as paraneoplastic manifestation in about 7% of cases, especially in lymphomas and tumors involving the digestive tract.

Particularities of the case consisted in the accidental discovery of the renal tumor, in spite of the lack of urinary syndromes. The present case highlights the importance of tumor screening in patients with atypical antibiotic-refractory skin ulcers.


Keywords


ultrasound, renal carcinoma, Pyoderma gangrenosum, paraneoplastic

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References


Baijens LW, Manni JJ. Paraneoplastic syndromes in patients

with primary malignancies of the head and neck: four cases

and a review of the literature. Eur Arch Otorhinolaryngol

;263:32-36.

Brunsting LA, Goeckerman WH, O’Leary PA. Pyoderma

gangenosum: clinical and experimental observations

in five cases occurring in adults. Arch Derm Syphilol

;22:655-680.

Crowson AN, Mihm MC Jr, Magro C. Pyoderma gangrenosum:

a review. J Cutan Pathol 2003:30:97-107.

Regnier-Rosencher E, Bizet N, Mery L. Pyoderma gangrenosum

associated with renal carcinoma. J Am Acad

Dermatol 2011;64:1208-1211.

Cosgarea I, Lovric Z, Körber A, Dissemond J. Successfull

treatment of refractory pyoderma gangrenosum with

ustekinumab only after excision of renal cell carcinoma. Int

Wound J 2016;13:1041-1042.

Solovan C, Smiszek R, Wickenhauser C, Chiticariu E. Postoperative

Pyoderma gangrenosum in association with renal

cell carcinoma and chronic lymphocytic leukemia. Infect

Dis Ther 2013,2:7580.

Aldaabil R, Peereboom D. Paraneoplastic Syndromes in

Renal Cell Carcinoma. In: Bukowski RM, Novick AC.

(eds). Renal Cell Carcinoma. Current Clinical Oncology.

Totowa, Humana Press 2000:135-145.




DOI: http://dx.doi.org/10.11152/mu-1751

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